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Moumoujus

ANGELICA KEISKEI CALLUS EXTRACT.

Valuable / ANTIMICROBIAL, ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

This plant-derived extract is a potent antioxidant and skin-conditioning agent. It helps enhance anti-aging effects and supports skin barrier function.

Summary

antioxidant antimicrobial skin-conditioning hair-conditioning

Science

Mechanism of Action

Primarily activates the NRF2 signaling pathway, which boosts cellular antioxidant responses and upregulates skin barrier proteins like filaggrin. It also offers antimicrobial and conditioning benefits for skin and hair.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

10%

Key findings

  1. 01 A 2025 MDPI study found 10% concentration enhances anti-aging effects, antioxidant capacity, and skin barrier by activating NRF2, showing no irritation in human patch tests.
  2. 02 ResearchGate in 2025 reported exosomes from this extract promote significant wound healing and filaggrin expression without irritation.

Transparency

Dusting Analysis

Not commonly dusted

No information available regarding dusting characteristics for this ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Water-soluble and stable during heat extraction up to 121°C, but requires storage in dark, dry environments. Exosome forms may need refrigeration.

Conflicts

  • strong oxidizing agents
  • high concentrations of alcohol (may precipitate proteins/polysaccharides)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

Although not formally reviewed by CIR, human patch tests (30+ participants) indicate it is non-irritating at standard usage levels. It is approved in the EU and global markets.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Angelica Keiskei Callus Extract is a valuable ingredient, demonstrating significant anti-aging, barrier-repair, and antioxidant benefits with low irritation risk across all skin types.

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