Science
Mechanism of Action
It functions by inhibiting UV-induced Matrix Metalloproteinases (MMPs) through MAPK pathway modulation, preventing collagen breakdown. Additionally, it stimulates Aquaporin 3 to enhance epidermal hydration and promotes collagen synthesis via TGF-β1.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies showed Angelica Archangelica extract reduced UVB-induced ERK and JNK phosphorylation, diminishing MMP expression and preventing collagen degradation.
- 02 Aqueous extract stimulated Aquaporin 3 (AQP3) expression in keratinocytes, improving skin hydration and promoting cell renewal.
Transparency
Dusting Analysis
Available research does not indicate this ingredient is commonly dusted in formulations.
The Formula
Formulation
Stability
Aqueous extracts are stable in a slightly acidic pH range (4.0-6.5). Heat-sensitive essential oil components should be incorporated during the cool-down phase below 40°C.
Conflicts
- Strong oxidizing agents
- Strong UV light (due to phototoxicity)
Safety
Safety Profile
Contains furocoumarins, which are phototoxic; use is restricted by IFRA in leave-on products. It is generally safe when formulated within specified limits and furocoumarin content is minimized.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Angelica Archangelica Extract is a valuable ingredient, offering significant anti-aging, hydrating, and soothing benefits, though careful formulation is needed to mitigate phototoxicity concerns.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources