Science
Mechanism of Action
This extract primarily inhibits matrix metalloproteinases (MMP-1, MMP-2) and enzymes like collagenase and elastase, which degrade the extracellular matrix. It also promotes Type I collagen synthesis and offers antioxidant, anti-inflammatory, and hyperpigmentation-improving effects.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 In vitro studies showed 0.01% decreased MMP-2 activity by 36.6% and increased Type I collagen synthesis by 55.5% in human dermal fibroblasts.
- 02 Cell-free assays demonstrated 1% inhibited collagenase activity by 50.4% and elastase activity by 30.9%, indicating significant anti-wrinkle effects.
Transparency
Dusting Analysis
Insufficient data suggests this ingredient is commonly dusted; it is typically used for its active properties at functional concentrations.
The Formula
Formulation
Stability
Rich in (Z)-ligustilide, the extract is sensitive to light and air, requiring storage in opaque, airtight containers. Root extracts may be stabilized in Butylene Glycol for better water miscibility.
Conflicts
- Strong oxidizing agents
- High heat during emulsification
Safety
Safety Profile
The CIR has not formally reviewed this ingredient. It may contain furanocoumarins, which are potentially photosensitizing and necessitate careful formulation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Angelica Acutiloba Leaf Oil Extract is a valuable multi-functional ingredient offering significant anti-aging, antioxidant, and brightening benefits for various skin types.
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