Science
Mechanism of Action
Its sarsasapogenin content stimulates adipocyte activity via PPAR-gamma, leading to increased volume. Additionally, nyasol and mangiferin inhibit MMP-1 for anti-wrinkle effects and suppress tyrosinase for brightening.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Sederma (Croda) Internal Clinical Trial
- 02 Cosmetics Journal (2023), 10(3), 73
- 03 Heliyon (2024), 10(19), e37935
Transparency
Dusting Analysis
With specific clinical evidence supporting its efficacy at 5% for targeted plumping, this ingredient is typically used at effective concentrations rather than for 'dusting' purposes.
The Formula
Formulation
Stability
Highly stable in anhydrous oil-based systems. In O/W emulsions, it should be added to the oil phase or during the cooling phase (<40°C) to prevent degradation of bioactive saponins.
Conflicts
- Strong oxidizing agents
- Extreme pH conditions (>8.0 or <3.0) may destabilize saponin structures
Safety
Safety Profile
While CIR has not formally reviewed it, the ingredient is widely used at concentrations up to 5% with an EWG low hazard rating.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Anemarrhena Asphodeloides Callus Extract is a valuable ingredient for targeted volume enhancement and anti-aging, with good safety and formulation characteristics.
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References
Sources