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ANACARDOYL SH-PENTAPEPTIDE-5 TRIPEPTIDE-1.

Valuable / ANTIOXIDANT, BLEACHING, SKIN PROTECTING

This synthetic fatty acyl peptide, derived from anacardic acid and a peptide chain, offers multifunctional benefits. It combines antioxidant, skin-lightening, and anti-aging properties for comprehensive skin improvement.

antioxidant skin-lightening skin protecting anti-aging collagen synthesis stimulation glycosaminoglycan synthesis stimulation

Science

It functions as an antioxidant and skin protectant. The Tripeptide-1 component stimulates collagen and GAG synthesis, while the anacardoyl moiety enhances penetration, providing additional bleaching and free-radical scavenging.


Research

Medium confidence
Effective range 0.0001–0.001%
Optimal

0.001%

Key findings

  1. 01 Cosmetic Ingredient Review (CIR) Safety Assessment 2014

Transparency

Commonly dusted
Min. effective
0.0001%
Red flag below
0.0001%

Due to its high potency and cost, this ingredient is effective at very low concentrations. Products may include it at sub-optimal levels to claim its presence without delivering full efficacy.


The Formula

Solubility
Both
Optimal pH 4 – 6.5
0 7 14

Stability

The anacardoyl conjugation improves oil compatibility, yet it is often supplied in aqueous-glycol solutions for easy integration into water phases. Avoid temperatures exceeding 40°C during formulation.

Conflicts

  • Strong oxidizing agents
  • Proteolytic enzymes
  • Extreme pH (<3.0 or >8.0)

Safety

CIR Status
Safe as used
Max tested
0.001%
Sensitization risk Low

The CIR Panel deemed Tripeptide-1 derivatives safe for use. Its high potency and cost result in very low typical use levels, ranging from 3-10 ppm.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This multifunctional peptide offers potent anti-aging, antioxidant, and brightening benefits, making it a valuable addition for comprehensive skin improvement.


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