Science
Mechanism of Action
Functions through dual pathways: upregulates moisture-related genes including HAS2 for hyaluronic acid synthesis, TJP1 for tight junction integrity, and FLG for filaggrin production, while providing antioxidant protection via alpha-bisabolol (16%) and camphor (17.6%) content that also delivers anti-inflammatory and soothing effects.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 Randomized controlled trial demonstrated significant increases in skin moisture and sebum production with reduced skin crease distance in working-age adults at 1% concentration after 120 minutes
- 02 In vitro keratinocyte studies confirmed upregulation of HAS2, TJP1, and FLG genes, validating barrier-repair mechanisms
Transparency
Dusting Analysis
Limited commercial availability and specific clinical validation at 1% suggests authentic inclusion rather than trace amounts for marketing purposes.
The Formula
Formulation
Stability
Contains volatile terpenes requiring sealed containers; demonstrated stability in gel and cream bases at both ambient and elevated temperatures
Synergies
- hyaluronic acid
- ceramides
- other barrier-supporting ingredients
Conflicts
- oxidizing agents
- high heat processing
Safety
Safety Profile
Semi-open patch testing shows no irritation; traditional use in Thai medicine and soap formulations suggests established safety profile despite lack of formal CIR review
Your Skin
Skin Compatibility
Our Assessment
Verdict
Well-researched botanical with proven moisturizing mechanisms and clinical validation, though limited commercial precedent requires careful formulation consideration.
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References
Sources