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AMODIMETHICONE.

Valuable CAS 71750-80-6 / ANTISTATIC, HAIR CONDITIONING

A cationic silicone polymer that selectively adheres to damaged skin areas through electrostatic attraction, forming a protective conditioning film. Its smart-binding technology delivers targeted repair while preventing product buildup, making it ideal for both skincare and primer applications.

antistatic hair conditioning skin conditioning

Science

Functions as an amine-functionalized silicone that becomes positively charged in water-based formulations. These cationic charges are magnetically drawn to negatively charged damaged skin surfaces, where it deposits a semi-permeable protective film that smooths texture, reduces friction, and provides long-lasting conditioning without over-accumulation.


Research

High confidence
Effective range 1–15%
Optimal

5%

Key findings

  1. 01 Human Repeat Insult Patch Test (83 participants) confirmed non-sensitizing properties at 5% concentration
  2. 02 Formulation studies at 1.0-15.0% demonstrate effective hair and skin conditioning with improved texture and silky feel

Transparency

Not commonly dusted

Legitimate functional ingredient with established safety profile and clear benefits at typical use concentrations


The Formula

Solubility
Water
Optimal pH 5.5 – 7
0 7 14

Stability

Supplied as cationic emulsion, stable in pH 5.5-7.0 range. Heat stable up to 50°C during mixing. May lose efficacy below pH 5 due to gradual hydrolysis.

Conflicts

  • Highly anionic surfactants
  • Anionic thickeners (Carbomer)
  • Strongly alkaline environments

Safety

CIR Status
Safe as used
Max tested
15%
Pregnancy
Safe
Sensitization risk Low

Large molecular weight prevents significant dermal absorption. Maximum 15% approved for rinse-off products, lower levels recommended for leave-on applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A well-researched multifunctional silicone that delivers targeted conditioning benefits with excellent safety profile across all skin types.


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