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Moumoujus

AMMONIUM TRICHLOROACETATE.

Valuable CAS 857169-57-4 / EXFOLIATING

A stabilized salt form of trichloroacetic acid that functions as a professional-grade biostimulator, penetrating to the dermal layer to trigger fibroblast activation and collagen synthesis. Unlike traditional TCA, this modified form delivers deep skin renewal benefits without causing surface frosting or epidermal damage, making it suitable for no-downtime treatments.

Summary

exfoliating skin-conditioning biostimulating

Science

Mechanism of Action

Penetrates the epidermis to reach dermal fibroblasts where it initiates a controlled skin stress response, stimulating collagen production and dermal remodeling. The ammonium salt formulation modulates acidity levels, preventing immediate protein denaturation while maintaining biostimulatory effects on deeper skin layers.

Research

Clinical Evidence

High confidence
Effective range 33–33%
Optimal

33%

Key findings

  1. 01 PRX-PLUS formulation at 33% concentration demonstrated significant improvements in skin tone, texture, and wrinkle reduction with enhanced radiance and no visible peeling
  2. 02 Clinical evaluation confirmed deeper dermal penetration targeting fibroblasts without epidermal stripping or traditional TCA-associated frosting effects

Transparency

Dusting Analysis

Not commonly dusted

Professional-grade ingredient typically used at clinically validated concentrations around 33% in specialized biostimulator formulations

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 5.5
0 7 14

Stability

Highly water-soluble crystalline compound with greater stability than free TCA in aqueous solutions. Susceptible to thermal decomposition at elevated temperatures, breaking down into chloroform and ammonium bicarbonate.

Synergies

  • citric acid
  • phytic acid
  • homocysteic acid

Conflicts

  • strong bases
  • oxidizing agents
  • alkaline ingredients
  • high heat exposure

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
33%
Sensitization risk Low

While not individually reviewed by CIR, parent compound TCA and related ammonium salts have established safety profiles. Professional guidance recommended for use at maximum concentrations. Regulated as exfoliating agent in EU markets.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A sophisticated biostimulatory ingredient that delivers professional-grade skin renewal benefits with minimal irritation when used at clinically validated concentrations.

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