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AMINOPROPYL MENTHYL PHOSPHATE.

Valuable CAS - / ANTI-SEBORRHEIC, ANTI-SEBUM, SKIN CONDITIONING

A stable menthol derivative, Aminopropyl Menthyl Phosphate effectively reduces excessive sebum production. It delivers a gentle cooling and soothing effect, making it ideal for managing oily and irritated skin conditions.

Anti-seborrheic Anti-sebum Skin conditioning

Science

This ingredient functions as an anti-seborrheic and anti-sebum agent by helping to regulate oil gland activity. Its phosphate ester structure enhances chemical stability and minimizes irritation compared to pure menthol.


Research

Medium confidence
Effective range 0.01–3%
Optimal

0.75%

Key findings

  1. 01 WO2012164061A2 (Cosmetic preparations against dandruff)

Transparency

Not commonly dusted

No data indicates this ingredient is commonly dusted in formulations.


The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

The phosphate ester bond provides improved chemical stability, allowing for easier incorporation into water-based products like mists and serums.

Synergies

  • Lauroyl Arginate Ethyl (LAE)

Conflicts

  • Strongly acidic environments (potential for hydrolysis)
  • Cationic surfactants (at very high concentrations, potential for complexation)

Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

While not formally reviewed by CIR, related menthol derivatives and phosphate esters are generally safe. Patents suggest a usage limit of 3% in topical formulations.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This stable menthol derivative effectively controls sebum and offers a cooling sensation with reduced irritation, making it valuable for oily and sensitive skin.


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References