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Moumoujus

AMINOPROPYL DIHYDROGEN PHOSPHATE.

Valuable CAS 1071-28-9 / SKIN CONDITIONING

Aminopropyl Dihydrogen Phosphate is an anti-aging agent that promotes collagen synthesis and fibroblast proliferation. It also functions to enhance the stability and delivery of other active ingredients when used in conjugated forms.

Summary

skin conditioning anti-aging collagen boosting skin brightening

Science

Mechanism of Action

This ingredient acts as a signaling molecule, stimulating fibroblast growth and Type I collagen production to improve skin density and reduce wrinkles. It can also serve as a phosphate donor, enhancing the efficacy and stability of conjugated active compounds like Vitamin C.

Research

Clinical Evidence

Medium confidence
Effective range 1–3%
Optimal

N/A

Key findings

  1. 01 KoreaScience: The Synthesis and Safety of 3-Aminopropyl dihydrogen phosphate, a New Anti-aging Agent
  2. 02 ResearchGate: Development of 5-[(3-Aminopropyl)phosphinooxy]-2-(hydroxymethyl)-4H-pyran-4-one

Transparency

Dusting Analysis

Not commonly dusted

No specific data suggests this ingredient is commonly 'dusted' or used at ineffective concentrations in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Stable in water-based systems within a slightly acidic to neutral pH range. It is best stored in a cool, dark place (2-8°C) and typically added to the water phase of emulsions.

Synergies

  • Vitamin C (Ascorbic Acid) for enhanced stability and skin lightening

Conflicts

  • Strong oxidizing agents
  • High pH environments (>7.0)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

While not formally reviewed by CIR, it is part of the generally safe alkyl phosphate class. Toxicity tests and Human Repeated Insult Patch Tests (HRIPT) demonstrate its safety at typical cosmetic concentrations.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This ingredient is a valuable asset for anti-aging and skin brightening, demonstrating significant potential for collagen synthesis and enhancing active ingredient stability.

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