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AMINOPROPANEDIOL.

Valuable CAS 616-30-8 / BUFFERING

Aminopropanediol is a versatile amino alcohol primarily used as a pH adjuster and buffering agent. In bioengineered forms, it can also function as a barrier-repairing active.

pH Adjuster Buffering Skin Conditioning Cleansing Agent

Science

It neutralizes acidic components to stabilize formula pH. Additionally, it can react with sebum fatty acids to aid follicular cleansing or mimic ceramides to support barrier function.


Research

High confidence
Effective range 1–2%
Optimal

1.5%

Key findings

  1. 01 Wroclaw Medical University (2020), published in NIH/MDPI (efficacy for acne-prone skin)
  2. 02 Cosmetic Ingredient Review (CIR) Amended Report (2009) (safety in finished products)

Transparency

Not commonly dusted

As a primary pH adjuster and buffering agent, this ingredient's functional concentration makes it generally unsuitable for dusting.


The Formula

Solubility
Water
Optimal pH 5.5 – 7
0 7 14

Stability

Highly hygroscopic, requiring airtight storage; it remains stable across a wide pH range, optimally adjusting formulas to pH 5.5-7.0.

Conflicts

  • N-nitrosating agents

Safety

CIR Status
Safe as used.
Max tested
10%
Sensitization risk Low

Avoid use with N-nitrosating agents to prevent the formation of carcinogenic nitrosamines.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A valuable, safe ingredient, highly effective for pH adjustment, with specific forms offering benefits for sebum management and barrier support.


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