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ALUMINUM SUCROSE OCTASULFATE.

Valuable CAS 54182-58-0 / SKIN CONDITIONING

This cytoprotective ingredient forms a physical barrier on damaged skin, effectively reducing irritation and promoting healing. It is well-suited for skin repair and barrier restoration across all skin types.

Skin conditioning Soothing Skin protecting

Science

It binds to positively charged proteins in compromised skin, creating a protective film. Additionally, it stabilizes heparin-binding growth factors like bFGF, which enhances angiogenesis and fibroblast proliferation for accelerated tissue repair.


Research

High confidence
Effective range 1–3%
Optimal

N/A

Key findings

  1. 01 A 1% concentration significantly reduced radiation-induced skin reactions and accelerated healing.
  2. 02 Topical 1% improved skin barrier recovery and reduced inflammation in irritant diaper dermatitis.
  3. 03 A 3% formulation enhanced granulation tissue formation and epithelialization in chronic skin ulcers.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Optimal stability is achieved in a slightly acidic to neutral pH range; pH below 3.0 can lead to undesirable polymerization and texture issues.

Conflicts

  • Highly alkaline environments
  • Strong cationic surfactants
  • Certain metal ions

Safety

CIR Status
Not reviewed
Sensitization risk Low

While not specifically reviewed by CIR, aluminum compounds are generally deemed safe by SCCS. Sucralfate exhibits negligible systemic absorption, contributing to its high safety profile for topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Aluminum Sucrose Octasulfate is a valuable ingredient for promoting skin healing and protection due to its cytoprotective action and low irritation profile.


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