Science
Mechanism of Action
This extract exerts its benefits through several key mechanisms. It contains kaempferol and coumarins, which contribute to its anti-inflammatory effects, potentially by modulating nitric oxide (NO) production pathways. Furthermore, like general Althaea Rosea extracts, it provides mucilage that forms a protective, moisture-retaining barrier on the skin. Antioxidants within the extract neutralize free radicals, mitigating oxidative stress and premature aging, while flavonoids support skin regeneration for a more even and revitalized complexion. These combined actions lead to significant soothing and moisturizing effects.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
While Althaea Rosea Callus Extract offers clear mechanistic benefits, specific clinical efficacy data, including optimal concentrations for human application, are not currently available. This lack of precise data for the callus extract itself, distinguishing it from general plant extracts, suggests a potential for 'dusting' where it might be included in formulations without specific, data-backed concentration targets for its claimed benefits. A related Althaea Rosea flower extract has been assessed as safe for cosmetic use up to 2%, but this does not directly translate to the callus extract's efficacy.
The Formula
Formulation
Stability
Though generally considered non-irritating, formulators should be aware that aesthetic, stability, or other issues may arise, which could potentially limit the extract's utility in certain formulations.
Safety
Safety Profile
Althaea Rosea Callus Extract has not undergone a specific safety assessment by CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety), and its FDA status for cosmetic use is not explicitly available. Dermal toxicity for this specific callus culture extract is reported as 'Not determined'. However, Althaea Rosea flower extract, a closely related ingredient, has been deemed unlikely to pose additional health risks for cosmetic use at concentrations up to 2%. General Althaea Rosea extracts are considered mild and typically do not cause adverse effects. Although Paula's Choice includes a general disclaimer about potential irritation for unrated ingredients, this is not a specific finding for the callus extract itself; overall, a low irritancy potential is expected.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Althaea Rosea Callus Extract is a valuable ingredient, offering significant anti-inflammatory, soothing, and moisturizing benefits rooted in established plant chemistry, though further specific clinical data on the callus extract's optimal concentrations is required for precise efficacy targeting.
Related
Similar Ingredients
Finding similar ingredients…