Science
Mechanism of Action
ALTHAEA OFFICINALIS CALLUS CULTURE EXTRACT functions primarily through its rich mucilage content, comprised of skin-smoothing polysaccharides such as glucuronic acid, rhamnose, and galactose. These compounds work to attract and retain moisture, effectively maintaining skin hydration by inhibiting enzymes that degrade hyaluronic acid. It also forms a protective barrier against environmental aggressors, while its anti-inflammatory and antioxidant properties help reduce redness, soothe irritation, protect against oxidative stress from UVA light, and support skin regeneration and barrier integrity.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 An in vitro study demonstrated that ethyl acetate extracts of Althaea officinalis calli exhibited anticancer activity on SH-SY5Y human neuroblastoma cells at concentrations ranging from 62.5 to 1000 µg/ml.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This extract is highly compatible with aqueous formulations, exhibiting optimal stability within a pH range of 5.0 to 6.5. Its water solubility makes it ideal for integrating into water-based products.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) has not specifically evaluated ALTHAEA OFFICINALIS CALLUS CULTURE EXTRACT, its shared CAS and EC numbers with Althaea Officinalis Root Extract suggest a comparable safety profile. The root extract is widely regarded as safe for cosmetic applications, demonstrating non-toxicity and minimal irritation potential, even for sensitive skin. The FDA has also recognized 'ALTHEA ROOT' as Generally Recognized As Safe (GRAS) for internal use as a flavoring. Adverse reactions are infrequent, though a patch test is recommended for individuals with known plant allergies.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly compatible ingredient, offering significant hydrating, soothing, and protective benefits, primarily inferred from its mucilage content and similarity to the well-researched Althaea Officinalis root extract.
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References
Sources