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ALTHAEA OFFICINALIS CALLUS CULTURE EXTRACT.

Valuable CAS 73049-65-7 / ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

This extract, derived from marshmallow plant callus cultures, is a multifunctional skincare ingredient celebrated for its hydrating, soothing, and protective properties. It works by attracting and retaining moisture, supporting the skin barrier, and offering antioxidant defense against environmental stressors.

skin conditioning antioxidant humectant skin protecting agent

Science

ALTHAEA OFFICINALIS CALLUS CULTURE EXTRACT functions primarily through its rich mucilage content, comprised of skin-smoothing polysaccharides such as glucuronic acid, rhamnose, and galactose. These compounds work to attract and retain moisture, effectively maintaining skin hydration by inhibiting enzymes that degrade hyaluronic acid. It also forms a protective barrier against environmental aggressors, while its anti-inflammatory and antioxidant properties help reduce redness, soothe irritation, protect against oxidative stress from UVA light, and support skin regeneration and barrier integrity.


Research

Low confidence
Effective range 62.5–1000%
Optimal

N/A

Key findings

  1. 01 An in vitro study demonstrated that ethyl acetate extracts of Althaea officinalis calli exhibited anticancer activity on SH-SY5Y human neuroblastoma cells at concentrations ranging from 62.5 to 1000 µg/ml.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 6.5
0 7 14

Stability

This extract is highly compatible with aqueous formulations, exhibiting optimal stability within a pH range of 5.0 to 6.5. Its water solubility makes it ideal for integrating into water-based products.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not specifically evaluated ALTHAEA OFFICINALIS CALLUS CULTURE EXTRACT, its shared CAS and EC numbers with Althaea Officinalis Root Extract suggest a comparable safety profile. The root extract is widely regarded as safe for cosmetic applications, demonstrating non-toxicity and minimal irritation potential, even for sensitive skin. The FDA has also recognized 'ALTHEA ROOT' as Generally Recognized As Safe (GRAS) for internal use as a flavoring. Adverse reactions are infrequent, though a patch test is recommended for individuals with known plant allergies.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

A highly compatible ingredient, offering significant hydrating, soothing, and protective benefits, primarily inferred from its mucilage content and similarity to the well-researched Althaea Officinalis root extract.


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