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ALPINIA OXYPHYLLA SEED EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Alpinia Oxyphylla Seed Extract is a botanical active renowned for its potent antioxidant and skin-brightening capabilities. Derived from the seeds of Alpinia oxyphylla, this extract actively combats oxidative stress, reduces hyperpigmentation, and demonstrates protective and anti-aging properties at a cellular level.

Summary

antioxidant skin-brightening anti-inflammatory

Science

Mechanism of Action

This extract functions as a multi-faceted agent, primarily by mitigating oxidative stress through the reduction of reactive oxygen species (ROS) and malondialdehyde (MDA), while simultaneously enhancing endogenous antioxidant enzyme activity. It exhibits anti-inflammatory effects and acts as a tyrosinase inhibitor, which directly impedes melanin synthesis, resulting in visible skin brightening. Furthermore, it protects cellular integrity against various forms of oxidative damage.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 At 100 μg/mL, the extract significantly prolonged lifespan by 23.44% in C. elegans, alleviated age-related declines, and enhanced stress resistance by decreasing ROS and MDA, and increasing antioxidant enzyme activities.
  2. 02 Organic extracts between 50-200 μg/mL protected PC12 cells against hydrogen peroxide-induced cytotoxicity in a concentration-dependent manner, indicating neuroprotective and antioxidant actions in vitro.
  3. 03 An ethanol extract from leaves and stems at 100 μg/mL exhibited strong antioxidant activities, achieving a DPPH free radical scavenging rate of 40.7% and an ABTS free radical scavenging rate of 90.4%.
  4. 04 At 200 μg/mL, specific isolated compounds demonstrated significant tyrosinase inhibitory activity (up to 74.7%) and concentration-dependent melanin production inhibition in B16 cells, suggesting strong skin brightening potential.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific cosmetic regulatory status from CIR, SCCS, or FDA has been found. However, the dry seed of A. oxyphylla is generally regarded as safe for human consumption as food or medicine, with an oral acute toxicity test showing no toxicity at 5,000 mg/kg.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Alpinia Oxyphylla Seed Extract is a valuable ingredient, offering proven antioxidant, skin-brightening, and anti-aging benefits to promote overall skin health and radiance.

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