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ALPINIA CALCARATA RHIZOME/ROOT EXTRACT.

Valuable CAS 90132-03-9 / SKIN CONDITIONING

Alpinia Calcarata Rhizome/Root Extract is a botanical active offering significant antioxidant and anti-inflammatory benefits, derived from its rich phytochemical composition. It demonstrates promise in calming reactive skin and potentially addressing uneven tone, positioning it as a multifaceted ingredient for precision skincare formulations.

Summary

Antioxidant Anti-inflammatory Skin conditioning Antimicrobial Skin Brightening (potential)

Science

Mechanism of Action

This extract operates through a multi-pronged mechanism, primarily attributed to its abundant phytochemicals, including polyphenols, tannins, flavonoids, and steroids. Its antioxidant capacity is established through hydrogen peroxide scavenging and enhancing reducing power. Anti-inflammatory effects are mediated by membrane stabilization and concentration-dependent inhibition of protein denaturation. Furthermore, the identification of hydroquinone, present in some rhizome extracts at up to 44.17±0.36%, suggests a potential mechanism for skin brightening. The extract also exhibits antibacterial and antifungal activities.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An emulgel containing 50 µg/mL of Alpinia calcarata essential oil demonstrated significant anti-inflammatory activity in vitro, inhibiting heat-induced hemolysis by 87.68 ± 0.35%. This activity was found to be highly concentration-dependent (r2 = 0.99).
  2. 02 In vitro evaluations of an ethanolic extract, across concentrations ranging from 25 to 400 µg/ml, confirmed both antioxidant activity (via hydrogen peroxide scavenging and reducing power) and anti-inflammatory activity (through concentration-dependent inhibition of protein denaturation).

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Oral administration of hot ethanol and hot water extracts of Alpinia calcarata rhizome in animal studies, at doses up to 1500 mg/kg/day for 42 consecutive days, reported no serious toxic effects on hepatic or nephritic function, blood counts, organ weights, or physiological functions. The ingredient is registered with an FDA UNII code (48F50O152S), and the INCI Beauty database indicates 'No penalty' in all categories.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Alpinia Calcarata Rhizome/Root Extract is a valuable botanical ingredient, offering confirmed antioxidant and anti-inflammatory benefits for sensitive skin, with potential for brightening and overall skin conditioning.

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