Science
Mechanism of Action
Rich in diarylheptanoids, it inhibits NF-κB and STAT1 pathways, reducing pro-inflammatory cytokines (TNF-α, IL-6) and nitric oxide. It boosts antioxidant enzymes, inhibits tyrosinase for anti-melanogenic effects, and balances skin flora to prevent blackheads.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Active diarylheptanoids are stable in hot water extractions and 50-80% ethanol mixtures, suitable for water-based lotions or stabilized emulsions.
Conflicts
- Strong oxidizing agents
- High heat (>100°C) for prolonged periods during formulation
Safety
Safety Profile
While CIR has not reviewed it, related Betulaceae family extracts are generally considered safe. In-vitro and in-vivo studies indicate very low toxicity and good human compatibility.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This versatile botanical extract is valuable for its significant anti-inflammatory, antioxidant, and skin-balancing benefits, suitable for a wide range of skin types.
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References
Sources