Science
Mechanism of Action
It inhibits pro-inflammatory cytokines, modulates fibroblast proliferation, and synthesizes collagen to prevent hypertrophic scarring. Its high flavonoid content also provides significant antioxidant and antimicrobial effects.
Research
Clinical Evidence
High confidence12%
Key findings
- 01 Topical application improved surgical scar height and symptoms (redness, itching, and pain) in Asian patients.
- 02 Showed significant wound healing activity in rat models, improving fibroblast count and reducing scar formation.
- 03 Demonstrated high stability and retained antioxidant activity (quercetin) over 90 days at 25°C, supporting its efficacy for scar management.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable at 25°C within pH 5.0-5.5; however, exposure to temperatures >40°C or refrigeration (4°C) may decrease antioxidant activity or cause quercetin precipitation.
Conflicts
- Strong oxidizing agents
- Highly alkaline environments (pH > 7.0)
Safety
Safety Profile
While not formally reviewed by CIR, this food-grade extract is widely used in commercial products up to 15% and is considered safe. Some raw forms may pose potential Category 2 skin irritancy.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Allium Cepa Skin Extract is a valuable, well-researched ingredient demonstrating significant efficacy in scar management, wound healing, and providing antioxidant and soothing benefits.
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