Science
Mechanism of Action
This ingredient operates through the combined actions of its two constituent compounds. The allantoin component actively soothes and protects the skin, facilitating the healing of minor damage, mitigating irritation and inflammation, and stimulating cellular regeneration. It also exerts a mild keratolytic effect, assisting in the gentle exfoliation of dead skin cells. Simultaneously, the ascorbate component, a stabilized Vitamin C derivative, functions as a powerful antioxidant, effectively neutralizing reactive oxygen species (ROS) that contribute to photoaging. Furthermore, it plays a critical role in supporting collagen synthesis, essential for maintaining skin structure, and aids in reducing hyperpigmentation to improve skin tone uniformity.
Research
Clinical Evidence
Low confidence2%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Allantoin Ascorbate is formulated for enhanced stability compared to pure L-ascorbic acid, demonstrating robustness in both dry powder form and solution. It exhibits resilience to heat, a significant advantage for formulation. While allantoin maintains stability across a pH range of 4.0–8.0, stabilized Vitamin C derivatives are most effective and stable in a mildly acidic environment, typically between pH 4.0 and 5.5. Therefore, the complex is optimally stable and functional within this mildly acidic to neutral pH range.
Synergies
- The co-delivery of allantoin and ascorbate offers synergistic benefits, combining enhanced skin repair, soothing, and protection with potent antioxidant defense and collagen support, surpassing the efficacy of individual components.
Safety
Safety Profile
The CIR Expert Panel has determined allantoin and its derivatives, including Allantoin Ascorbate, to be safe for use in cosmetic applications. Allantoin is recognized by the FDA as an active ingredient in OTC skin protectant drug products at concentrations ranging from 0.5% to 2%. Although comprehensive data specifically for Allantoin Ascorbate's use and concentration was noted as a gap in the CIR review, the safety of its individual components (allantoin and ascorbic acid) is well-established. EWG Skin Deep identifies low concerns for Allantoin Ascorbate regarding cancer, allergies/immunotoxicity, and developmental/reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Allantoin Ascorbate is a valuable multi-functional ingredient, offering significant antioxidant, soothing, and reparative benefits for the skin, making it suitable across all skin types.
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References
Sources
- cosmileeurope.eu ↗
- skinsort.com ↗
- clevelandclinic.org ↗
- specialchem.com ↗
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- incidecoder.com ↗
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- mitochon.it ↗
- nih.gov ↗
- researchgate.net ↗
- ewg.org ↗
- google.com ↗
- cosmeticscience.net ↗
- bpderma.com ↗