Science
Mechanism of Action
This pulp extract exerts its effects primarily through its high concentration of polyphenols, malic, and citric acids, which function as robust free radical scavengers. This antioxidant action effectively neutralizes oxidative damage caused by species like superoxide and hydroxyl radicals. Additionally, its proven antimicrobial capabilities against a spectrum of multi-resistant bacterial strains and fungi suggest a mechanism for reinforcing skin barrier integrity and managing microbial imbalances.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated significant antioxidant activity, with 15.43% free radical scavenging at 0.05 mg/ml, escalating to 96.78% at 0.8 mg/ml.
- 02 Achieved a 74.30% DPPH clearance rate at a concentration of 2.0 mg/ml.
- 03 Showed targeted radical protection, clearing 54.9% of superoxide radicals at 300 µg/ml and 86.4% of hydroxyl radicals at 40 µg/ml.
- 04 Exhibited antimicrobial action against multi-drug resistant Pseudomonas aeruginosa, with bacteriostatic effects observed at 187.5 mg/mL and bactericidal activity at 375 mg/mL (aqueous extract).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract demonstrates inherent stability within acidic conditions, aligning with its natural pH of 3.5. This pH is favorable for optimizing the stability and efficacy of its key bioactive compounds, such as anthocyanins.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific safety assessment, classifying this ingredient as having 'insufficient data.' While 'ALIBERTIA PATINOI FRUIT EXTRACT' is listed in Cosmile Europe without specific use restrictions, *in vitro* studies raise significant concerns. Concentrations ranging from 0.05 to 187.5 µg/mL of an aqueous extract were found to be toxic to human conjunctive (WKD) cells and exhibited anti-proliferative effects on colon cancer (Caco-2) cell lines. These cellular toxicity findings require cautious consideration for topical application concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While ALIBERTIA PATINOI PULP EXTRACT presents promising *in vitro* antioxidant and antimicrobial benefits across various concentrations, the current lack of comprehensive safety data from regulatory bodies and observed *in vitro* cellular toxicity classify its overall suitability as 'insufficient-data' for definitive recommendation in precision skincare formulations.
Related
Similar Ingredients
Finding similar ingredients…