Science
Mechanism of Action
Aldioxa operates through a dual mechanism derived from its components. Its aluminum hydroxide fraction acts as an astringent, forming a protective barrier and reducing inflammation by precipitating proteins. Concurrently, the allantoin component provides keratolytic benefits, facilitating the removal of dead skin cells, and promoting healthy tissue regeneration alongside moisturizing properties to maintain skin hydration. This synergy enhances wound healing by increasing fibroblast proliferation and potentially offers mild antimicrobial action through aluminum ions.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrates mild antiperspirant effects, effectively reducing sweat production in foot and antiperspirant products.
- 02 Reduces wetness and irritation, proving beneficial in baby products for preventing and soothing diaper rash.
- 03 Exhibits a slight astringent effect on inflamed acne lesions, promoting their healing and providing a soothing sensation.
- 04 Supports the healing of inflamed and bleeding gums while offering soothing and pain-relieving effects on sensitive teeth in oral care applications.
Transparency
Dusting Analysis
No specific data regarding 'dusting' or 'dusting threshold' for Aldioxa was found in the research.
The Formula
Formulation
Stability
Aldioxa maintains stability across a pH range of 3 to 8 and tolerates processing temperatures up to 80°C. It is not soluble in water or alcohols and is practically insoluble in diethyl ether, though it dissolves in dilute hydrochloric and nitric acids.
Conflicts
- Strong acids
- Exfoliants
Safety
Safety Profile
The CIR Expert Panel indicated a need for further data, including genotoxicity and phototoxicity, to finalize a comprehensive safety assessment. However, human volunteer studies have demonstrated that Aldioxa is non-sensitizing and non-irritating at concentrations of 2% (in suspension) and 4% (in ointment). No specific SCCS opinion defining maximum safe concentrations for Aldioxa as an individual ingredient across all cosmetic categories has been identified. Caution is advised for individuals with known allergies to aluminum or allantoin, and when applying to broken or severely damaged skin due to potential increased systemic absorption.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Aldioxa offers promising soothing, protective, and wound-healing benefits across various skin types at concentrations up to 2%, but its full safety profile awaits further data from the CIR Expert Panel.
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References
Sources