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ALCHEMILLA ALPINA EXTRACT.

Valuable CAS 90320-27-7 / SKIN CONDITIONING

Alchemilla Alpina Extract, derived from the alpine lady's mantle, is a robust botanical ingredient lauded for its potent antioxidant and anti-inflammatory capacities. Its rich composition helps combat oxidative stress, soothe skin irritation, and contributes to enhanced skin regeneration and barrier strength. This multifaceted extract also offers astringent properties for improved skin texture and may support overall skin elasticity and hydration.

Summary

Antioxidant Anti-inflammatory Astringent Skin conditioning Wound Healing Skin Regenerating Elasticity Enhancer Hydrator Barrier Strengthening Antibacterial Anti-aging Sebum Regulator Pore Minimizer

Science

Mechanism of Action

Alchemilla Alpina Extract operates through a complex blend of active compounds, including flavonoids, tannins, and phenolic acids. These constituents primarily neutralize free radicals, thereby minimizing oxidative damage and facilitating normal protein synthesis within the skin. The extract exhibits anti-inflammatory effects, which can calm and soothe irritated skin and potentially support acne treatment. Its astringent qualities, attributed to tannins and salicylic acid, contribute to temporary pore tightening and regulation of sebum production. Furthermore, Alchemilla Alpina Extract is reported to promote wound healing, stimulate skin tissue regeneration, and aid in maintaining skin elasticity and hydration, thus reinforcing the skin barrier. It also demonstrates antibacterial efficacy against Gram-positive skin pathogens and may confer anti-aging benefits through its inhibitory actions on elastase and tyrosinase, coupled with its capacity to enhance collagen production.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1-2%

Key findings

  1. 01 In-vitro analyses of Alchemilla Alpina Extract demonstrated significant antioxidant capability, achieving 45.4% to 94.4% inhibition of DPPH scavenging, with the degree of inhibition being concentration-dependent.
  2. 02 In-vivo double-blind randomized studies using creams formulated with Alchemilla vulgaris extract at 1% and 2% concentrations exhibited notable anti-irritant effects on human skin irritated by sodium lauryl sulphate (SLS). This research underscored the extract's safety and efficacy in preserving normal skin properties; however, it should be noted this specific finding pertains to Alchemilla vulgaris, a related species.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Optimal pH ranges for Alchemilla Alpina Extract's stability are not explicitly documented. Extracts prepared using organic vegetable glycerin and free of alcohol are mentioned as suitable formulations.

Conflicts

  • Elevated concentrations of tannins within Alchemilla extracts may lead to skin sensitivity and dryness, potentially accentuating the appearance of fine lines and wrinkles due to dehydration. For individuals with sensitive or dry skin types, formulators should consider utilizing tannin-removed extracts.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Specific safety evaluations by CIR, SCCS, or FDA for Alchemilla Alpina Extract are not available. Nevertheless, extracts from the related species, Alchemilla vulgaris, have demonstrated in-vivo safety and significant anti-irritant effects in topical formulations at 1-2% concentrations. It is important to acknowledge that high concentrations of tannins in Alchemilla extracts could potentially induce skin sensitivity and dryness.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Alchemilla Alpina Extract presents itself as a valuable botanical for skincare, offering a broad spectrum of antioxidant, anti-inflammatory, and restorative benefits, though careful formulation to manage tannin content is advisable.

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