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ALANINE.

Valuable CAS 302-72-7 / 56-41-7 / ANTISTATIC, FRAGRANCE, HAIR CONDITIONING, SKIN CONDITIONING

Alanine, a vital non-essential amino acid, is a significant constituent of the skin's Natural Moisturizing Factors (NMF). It functions as a potent humectant, drawing and retaining water to significantly boost skin hydration, leading to a plumper, smoother complexion. Beyond hydration, Alanine fortifies the skin barrier and supports collagen production for noticeable anti-aging benefits.

Hydrates the skin Enhances skin barrier function Supports collagen synthesis Reduces fine lines and wrinkles Improves skin elasticity Soothes inflammation Skin conditioning Hair conditioning Building block for skin proteins Antistatic Masking

Science

As a prominent component of the skin's Natural Moisturizing Factors (NMF), Alanine effectively binds water molecules, functioning as a humectant to deliver profound hydration. Its small molecular size facilitates deeper penetration, enhancing the skin's natural barrier function by fortifying its defenses against environmental stressors and minimizing trans-epidermal water loss. Furthermore, Alanine actively promotes collagen synthesis, contributing to a reduction in the appearance of fine lines and wrinkles and an improvement in skin elasticity. It also possesses calming properties, helping to soothe inflammation and stabilize the skin's overall condition.


Research

High confidence
Effective range N/A
Optimal

3%

Key findings

  1. 01 Topical application of alanine significantly enhances skin hydration, strengthens barrier function, and contributes to anti-aging outcomes through collagen support.
  2. 02 A 3% NMF Complex, which includes Alanine, demonstrated sustained hydration for up to 72 hours, improved skin barrier integrity, and calming effects without pore occlusion, suitable even for oily skin.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5.7 – 6.7
0 7 14

Stability

Alanine produces a clear, colorless solution, optimally stable within a pH range of 5.7 to 6.7. Amino acids, as a class, typically perform best in formulations with a pH between 5 and 8.


Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has determined Alanine to be safe for use at current practices. While its overall sensitization risk is low, caution is advised as very high concentrations may induce irritation or allergic reactions in individuals with heightened sensitivity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Alanine is a valuable amino acid that provides multi-functional benefits, including significant hydration, robust barrier support, and collagen-boosting anti-aging effects across all skin types.


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