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AKEBIA QUINATA STEM EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Akebia Quinata Stem Extract is a botanical active, rich in potent antioxidants like isochlorogenic acid C, that offers comprehensive anti-aging benefits. It works to visibly firm skin, reduce the appearance of wrinkles, calm redness, and enhance overall skin radiance and hydration.

Summary

Antioxidant Anti-aging Skin conditioning Soothing Redness reduction Firming Hydration Anti-glycation Collagen protection Fibrillin stimulation

Science

Mechanism of Action

This extract operates via multiple pathways to improve skin health and appearance. Its primary action involves potent antioxidants, such as isochlorogenic acid C, which neutralize free radicals, thereby minimizing oxidative stress and providing soothing benefits to reduce redness. It actively helps diminish the visible signs of aging by inhibiting matrix metalloproteinases, enzymes responsible for collagen degradation, which contributes to maintaining skin's firm look and feel. Furthermore, it protects fibroblasts from premature aging induced by Advanced Glycation End Products (AGEs), decreases intracellular Reactive Oxygen Species, and exhibits confirmed anti-glycation activity. It also stimulates the expression of fibrillin-1 for improved skin structure and boosts the production of 'urea', a natural moisturizing factor, to enhance intrinsic hydration. Triterpene glycosides further contribute to its moisturizing and free radical scavenging properties.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–5%
Optimal

N/A

Key findings

  1. 01 Clinical application at 0.5-2% concentrations has been shown to visibly reduce wrinkles by decreasing collagen-degrading enzymes (matrix metalloproteinases) and supporting skin firmness. This range also provides soothing and redness-reducing benefits due to potent antioxidants like isochlorogenic acid C.
  2. 02 Studies using 1-5% concentrations demonstrate multi-target anti-aging effects, including protection against fibroblast aging induced by AGEs, reduction of intracellular Reactive Oxygen Species, anti-glycation activity in a human skin explant model, and stimulation of fibrillin-1 expression for healthier, radiant skin.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Marker compounds within Akebia quinata extract showed varying stability, with some remaining stable for over 30 days at 5°C and room temperature.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While Akebia Quinata Stem Extract specifically lacks a CIR, SCCS, or FDA safety review, related Akebia Extract BG, which contains Akebia quinata or trifoliata stem extract, has undergone nine types of safety tests since 1997, demonstrating a verified safety profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Akebia Quinata Stem Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-aging, firming, soothing, and hydrating benefits for a wide range of skin types with a low risk of irritation.

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