Science
Mechanism of Action
It actively inhibits MMP-1 and tyrosinase, promotes collagen synthesis, and reduces oxidative stress by 17-35%. Its anti-inflammatory action also calms the skin by suppressing TNF-α and IL-6 cytokines.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 A 0.5% extract of Ajuga reptans (related species) significantly improved skin hydration, elasticity, and reduced pore size and hyperpigmentation after 60 days.
- 02 In vitro testing (100 µg/mL) confirmed increased pro-collagen type-1 synthesis and inhibition of collagen-degrading MMP-1 expression.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Extracts are generally stable in W/O and O/W emulsions, best maintained at skin-neutral pH. High ecdysterone content is sensitive to temperatures over 60°C during formulation.
Conflicts
- Strong oxidizing agents
- Extreme pH conditions (highly acidic or alkaline)
Safety
Safety Profile
While not specifically reviewed by CIR, related Ajuga species demonstrate high cell viability. Topical application risks are not documented, though high oral doses are linked to renal toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional extract is valuable for its antioxidant, anti-aging, and brightening effects, suitable for all skin types with low irritancy.
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