Science
Mechanism of Action
It acts by suppressing NLRP3 inflammasome activation via the NF-κB signaling pathway and scavenging intracellular ROS, providing significant anti-inflammatory effects. Additionally, it stimulates cellular proliferation and collagen synthesis, and its chromenes and flavonoids exhibit antimicrobial activity against P. acnes.
Research
Clinical Evidence
Medium confidence10%
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Ethanolic and methanolic extracts are common, with components soluble in both oil and water. It is sensitive to light and high temperatures, requiring storage at 4°C for optimal stability.
Conflicts
- Strong oxidizing agents
- Strongly alkaline environments (pH > 8.0)
Safety
Safety Profile
Safety data for cosmetic use is limited; concerns exist regarding pyrrolizidine alkaloids (PAs), which are hepatotoxic if ingested, but topical risk is poorly defined. INCI Beauty generally assigns 'No penalty'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ageratum Conyzoides Leaf Extract is a valuable ingredient due to its proven wound healing, anti-inflammatory, and antimicrobial benefits, with low irritancy and broad skin compatibility.
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