Science
Mechanism of Action
Primarily, this extract inhibits collagenase (IC50: 29.63 μg/mL) and elastase, preserving skin integrity. It also reduces melanin production by inhibiting tyrosinase (IC50: 6.17 μg/mL), provides radical-scavenging antioxidants (phlorotannins), and offers hydration via polysaccharides.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies show potent inhibitory activity against collagenase (IC50: 29.63 μg/mL), elastase (IC10: 16.13 μg/mL), and tyrosinase (IC50: 6.17 μg/mL), indicating strong anti-aging and skin-brightening potential.
- 02 Extract demonstrates significant antioxidant and anti-inflammatory effects in LPS-induced RAW 264.7 macrophages, reducing oxidative stress and inflammatory markers.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The active enzymes and phlorotannins in the extract maintain stability within a pH range of 6-9. It is commonly extracted using polar solvents like ethanol/water.
Conflicts
- Strongly acidic environments (pH < 4)
- Oxidizing agents
Safety
Safety Profile
The CIR 'Brown Algae-Derived Ingredients' safety assessment (2019/2022) concluded it as safe for current uses, with no observed sensitization in hydroglycolic solutions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Agarum Cribrosum Extract is a valuable, multi-functional ingredient offering significant anti-aging, brightening, antioxidant, and moisturizing benefits with excellent skin compatibility.
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