Science
Mechanism of Action
This extract functions as an antioxidant and immunomodulator, inhibiting melanogenesis by suppressing tyrosinase activity and nitric oxide production. It stimulates collagen synthesis and upregulates genes for hyaluronic acid and aquaporins, enhancing hydration and barrier function.
Research
Clinical Evidence
High confidence0.01%
Key findings
- 01 Inhibited melanin synthesis, increased collagen synthesis, and upregulated hyaluronan-2, 3 and aquaporin-3 synthase genes in human skin cells.
- 02 Reduced melanin content by up to 57% in melanocytes by suppressing tyrosinase activity and nitric oxide production.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Primarily water-soluble, contains heat-stable polysaccharides, but active phenolic compounds can degrade with extended high heat exposure. Store away from direct light to prevent oxidation.
Conflicts
- Strong oxidizing agents
- High concentrations of alcohol
Safety
Safety Profile
Generally recognized as safe for food, but long-term topical application data is limited. In vitro studies show cytotoxicity above 0.1% for pure extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Agaricus Blazei Extract is a valuable ingredient, demonstrating significant efficacy in skin brightening, hydration, and anti-aging at low concentrations, coupled with a favorable safety profile.
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References
Sources