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AFRAMOMUM MELEGUETA SEED EXTRACT.

Valuable CAS 90320-21-1 / SKIN CONDITIONING

This extract, derived from Grains of Paradise, activates skin's TRPV1 channels to enhance microcirculation and induce a mild warming sensation. It also offers significant anti-inflammatory and antioxidant benefits for comprehensive skin conditioning.

skin conditioning soothing antioxidant anti-inflammatory promotes localized circulation

Science

Its vanilloid compounds activate TRPV1 channels, stimulating microcirculation and a thermogenic sensation. Additionally, it reduces inflammation by inhibiting COX-2 and offers potent antioxidant protection by scavenging free radicals.


Research

High confidence
Effective range 0.05–5%
Optimal

0.2%

Key findings

  1. 01 Topical use at 1.0%-5.0% promotes localized circulation and a mild warming sensation.
  2. 02 Effective at 0.05%-3.0% for alleviating itching and inflammation, with 0.2%-3.0% preferred for efficacy.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 3 – 8
0 7 14

Stability

The extract maintains stability across a broad pH range (3.0-8.0) and integrates well into emulsions and gels. Active vanilloids are moderately soluble in oils and alcohols, while aqueous extracts offer antioxidant properties.

Conflicts

  • Strong oxidizing agents
  • High concentrations of ethanol

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Moderate

Recognized as safe for food use by the FDA, it is considered safe in cosmetic applications up to 5%. Individuals with hypersensitivity to ginger or cardamom should exercise caution due to potential transient tingling above 8%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Aframomum Melegueta Seed Extract is a valuable ingredient for its ability to enhance microcirculation, soothe inflammation, and provide antioxidant protection across various skin types.


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