Science
Mechanism of Action
This extract primarily inhibits matrix metalloproteinases like collagenase and elastase, preventing structural protein breakdown. Its rich content of polyphenols and polyacetylenes provides potent antioxidant protection and modulates inflammatory pathways.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Inhibited collagenase and elastase enzymes by over 70% and promoted keratinocyte/fibroblast proliferation at 5% concentration.
- 02 Demonstrated cytocompatibility and significantly stimulated cell migration and regeneration at concentrations at or above 5%.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Extracts are sensitive to high temperatures, which can cause thermal degradation of polyacetylenes. Stability is enhanced when formulated in water/glycerol or ethanol-based systems.
Conflicts
- Strong oxidizing agents
- High heat (>80°C during formulation)
Safety
Safety Profile
Generally considered safe based on historical folk use and low cell toxicity. While high oral doses of falcarinol can be neurotoxic, topical use at cosmetic levels shows no reported adverse effects.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted botanical extract is valuable for anti-aging and regenerative formulations due to its proven enzyme inhibition, antioxidant properties, and broad skin compatibility.
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References
Sources