Science
Mechanism of Action
This extract confers dermal benefits through diverse biochemical actions. It effectively counters photoaging by mitigating UVB-induced reactive oxygen species (ROS) production, concurrently inhibiting the phosphorylation of JNK, ERK, and p38, and preventing AP-1 complex formation. The extract enhances skin elasticity by stimulating the synthesis of Type I collagen, elastin, and hyaluronic acid synthase, while simultaneously downregulating detrimental matrix metalloproteinases (MMP-1, MMP-3, and MMP-9). Furthermore, it strengthens the skin barrier through increased expression of filaggrin, HAS1, and HAS2, and promotes skin transparency by reducing protein carbonylation in the stratum corneum.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The optimal pH for the stability of Actinidia Polygama Leaf/Stem Extract in cosmetic formulations is not explicitly defined in the available research. However, an optimized pH of 8 was reported for silver nanoparticle synthesis utilizing an aqueous extract of Actinidia polygama leaves.
Safety
Safety Profile
While a specific Cosmetic Ingredient Review (CIR) or SCCS assessment for Actinidia Polygama Leaf/Stem Extract is not available, the related Actinidia Polygama Fruit Extract has a generally recognized good safety profile and is deemed suitable for most users. Rare instances of allergic reactions may occur in individuals with heightened sensitivity to botanical extracts; therefore, a precautionary patch test is advisable.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Actinidia Polygama Leaf/Stem Extract is a valuable ingredient, offering broad-spectrum benefits including significant anti-photoaging, barrier reinforcement, and soothing properties, suitable for a wide range of skin types.
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References
Sources