Science
Mechanism of Action
This extract reduces inflammation by inhibiting COX-2 catalyzed prostaglandin biosynthesis and suppressing nitric oxide production. Its strong antioxidant action stems from abundant acetophenones, flavonoids, and phenolics, which effectively scavenge free radicals.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 Concentrations from 0.1% - 5% significantly inhibited COX-2 and prostaglandin biosynthesis, reducing edema by up to 78% in animal models.
- 02 At 100 µg/mL (0.01%), the extract exhibited 79% radical scavenging activity in DPPH assays, primarily due to its high phenolic and flavonoid content.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stable in aqueous and hydro-ethanolic systems, optimal stability is maintained with air-tight, light-protected packaging to prevent phenolic compound oxidation.
Conflicts
- Strong oxidizing agents
- Strongly alkaline environments (pH > 8.0)
Safety
Safety Profile
Although not formally reviewed by CIR or SCCS, acute toxicity studies on crude leaf extracts indicate a high safety margin with no significant toxicity at standard dosages.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable botanical active providing robust anti-inflammatory and antioxidant benefits, suitable for all skin types with low irritancy and comedogenicity.
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