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ACRONYCHIA PEDUNCULATA BARK EXTRACT.

Valuable CAS - / SKIN CONDITIONING

This botanical extract demonstrates multi-functional benefits, including potent antibacterial activity, significant antioxidant capacity, and anti-inflammatory properties. It also offers potential for skin brightening and anti-aging through tyrosinase inhibition.

Skin conditioning Antioxidant Soothing Antibacterial Skin brightening Anti-aging

Science

Its efficacy stems from acetophenones, alkaloids, and flavonoids, which inhibit pro-inflammatory mediators and suppress oxidative stress. It further intervenes in melanin synthesis via tyrosinase inhibition and offers antimicrobial protection against skin pathogens.


Research

Medium confidence
Effective range 0.1–1%
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrate potent antibacterial activity against S. aureus, significant antioxidant capacity, and anti-inflammatory properties by inhibiting COX-2 and NO production at 0.1%-1.0% concentration.
  2. 02 Phytochemical analysis reveals acetophenone derivatives with potential anti-proliferative and tyrosinase inhibitory activity, suggesting benefits for skin brightening and anti-aging.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 4.5 – 6.5
0 7 14

Stability

Volatile oils and phenolic compounds within the extract are sensitive to high temperatures and prolonged light exposure. Aqueous-glycolic bases enhance cosmetic stability for formulation.

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments (pH > 8.0)

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

No formal CIR safety assessment is available. It is generally well-tolerated at low concentrations and listed as a skin conditioning agent in EU CosIng and US PCPC.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This multi-functional extract is a valuable ingredient for addressing various skin concerns, including aging, inflammation, hyperpigmentation, and microbial imbalances.


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