Science
Mechanism of Action
It activates the Wnt/β-catenin signaling pathway, increasing β-catenin transcription and stimulating stem cell activity in dermal papilla cells. Additionally, it provides skin conditioning through potential anti-inflammatory and antioxidant effects.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro and mouse studies demonstrated significant activation of the Wnt/β-catenin pathway, promoting neural progenitor cell differentiation and increasing ALP activity in human dermal papilla cells, leading to anagen hair growth induction.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Heat-sensitive, should be added below 40°C during formulation. Optimal stability is in neutral to slightly alkaline environments (pH 7.0-7.5).
Conflicts
- High heat
- Strongly acidic environments
Safety
Safety Profile
Listed in EU CosIng and Chinese IECIC. While Aconitum species contain toxic alkaloids if ingested, cosmetic extracts are processed to minimize this risk, though specific topical safety limits remain unestablished by major bodies like CIR.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This extract shows promising hair growth and skin conditioning properties, but further research is needed to establish specific topical safety limits.
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References
Sources