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ACETYLCYCLOPENTANONE.

Questionable CAS 1670-46-8 / PERFUMING

Acetylcyclopentanone acts as a dicarbonyl scavenger, chelating agent, and perfuming ingredient. It offers potential antioxidant, antibacterial, and antifungal benefits for the skin.

perfuming antioxidant chelating agent antibacterial antifungal

Science

It scavenges α,β-unsaturated aldehydes, protecting against oxidative stress-induced cell damage. It also disrupts membrane permeability and inhibits specific enzyme pathways like carbonic anhydrase, contributing to antimicrobial effects.


Research

Low confidence
Effective range 0.46–21.05%
Optimal

N/A

Key findings

  1. 01 Exhibited fungistatic activity against Candida albicans at 0.46% as a component of Bursera morelensis essential oil.
  2. 02 Demonstrated significant inhibitory activity against Carbonic Anhydrase enzymes at 21.05% as a major constituent of Mentha longifolia essential oil.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 4.5 – 7.5
0 7 14

Stability

Stable under neutral to slightly alkaline conditions (pH 4.5-7.5). Avoid strong acids or extended room temperature exposure as it is prone to polymerization.

Conflicts

  • Strong oxidizing agents
  • Strong reducing agents
  • Strong bases
  • Mineral acids

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The parent compound, cyclopentanone, can be narcotic at high concentrations and is a potential skin irritant when pure. It is listed in the EU Cosmetic Inventory as a perfuming ingredient.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

While exhibiting promising antioxidant and antimicrobial mechanisms, the lack of comprehensive safety data and direct skincare efficacy studies for this isolated ingredient warrants caution.


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References