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ACETYL TRIPEPTIDE-74 AMIDE.

Valuable / SKIN CONDITIONING

Acetyl Tripeptide-74 Amide is a potent biomimetic lipo-peptide clinically shown to reduce fine lines and wrinkles. It offers soothing, anti-aging, and skin conditioning benefits by protecting the skin's extracellular matrix.

soothing anti-aging skin conditioning anti-inflammatory anti-photoaging

Science

This peptide inhibits NF-kB, suppressing pro-inflammatory responses, and reduces UV-induced MMP-1 expression. This dual action prevents procollagen degradation, providing anti-photoaging protection and maintaining skin structure.


Research

High confidence
Effective range N/A
Optimal

0.005%

Key findings

  1. 01 A clinical study using a serum cocktail containing 0.005% Acetyl Tripeptide-74 Amide demonstrated a 40% improvement in fine lines and 23% in wrinkles over 24 weeks.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Highly stable at room temperature as a raw material, and in formulations, it maintains stability for up to 24 months. It is water-soluble, electrolyte-tolerant, and compatible with most aqueous systems within its optimal pH range.

Conflicts

  • Strong oxidizing agents
  • Highly acidic (pH < 3.5) or highly alkaline (pH > 8.0) environments

Safety

CIR Status
Not reviewed
Max tested
0.01%
Sensitization risk Low

While not specifically reviewed by CIR, comparable acetylated amides have been deemed safe up to 0.005%. Supplier data indicates high purity and non-irritating profiles in patch testing.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Acetyl Tripeptide-74 Amide is a valuable anti-aging and soothing peptide, clinically proven to reduce wrinkles and protect skin from degradation.


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