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ACETYL TRIPEPTIDE-1.

Valuable CAS - / SKIN CONDITIONING

A synthetic signal peptide known for its anti-aging and skin-regenerating properties. It significantly enhances skin firmness, reduces wrinkles, and diminishes the appearance of dark circles.

skin conditioning cell-communicating ingredient

Science

Mimicking natural GHK fragments, it signals fibroblasts to boost synthesis of essential extracellular matrix proteins like collagen and elastin. This peptide also activates skin repair and inhibits collagen-degrading enzymes.


Research

High confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 At 3%, a visible reduction in dark circles and under-eye bags was observed due to stimulated collagen and elastin production.
  2. 02 In vivo studies at 1-5% demonstrated significant improvements in skin firmness and reduced wrinkle depth through enhanced ECM protein synthesis.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3.5 – 6.5
0 7 14

Stability

This heat-sensitive peptide should be added during the cooling phase (below 40°C). Raw material storage requires refrigeration (4-8°C).

Conflicts

  • Strong oxidizing agents
  • Extreme pH levels outside 3.5-6.5
  • High temperatures (>40°C)

Safety

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

The CIR Expert Panel found Tripeptide-1 and its derivatives safe. Formulations typically contain 1-5% of a peptide solution.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A valuable peptide for anti-aging and skin regeneration, effectively improving firmness, reducing wrinkles, and addressing under-eye concerns across all skin types.


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