Science
Mechanism of Action
Targets the proteoglycan Lumican, stimulating its synthesis along with Collagen Type I. This facilitates proper collagen fiber assembly and anchoring, improving dermal structure.
Research
Clinical Evidence
High confidence0.0025%
Key findings
- 01 0.0015%–0.0025% pure powder increased lumican synthesis by 115% and organized collagen fibers, leading to increased dermal density.
- 02 A 0.1% Dermican liquid blend treatment resulted in visibly thicker and firmer skin for 17 female volunteers compared to placebo.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stable within typical cosmetic pH range of 4.0-6.0 for 2+ years with proper storage. It is sensitive to extreme heat, strong oxidizing agents, and strong acids/bases.
Conflicts
- Strong oxidizing agents
- Strong acids/bases
- Proteolytic enzymes
Safety
Safety Profile
While not formally CIR reviewed, it's considered safe for cosmetic use up to 10% (as a commercial blend). Raw material SDS classifies it as non-hazardous.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This peptide is a valuable asset for anti-aging and firming formulations, demonstrably improving skin density and firmness through targeted protein synthesis.
Related
Similar Ingredients
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References
Sources