Science
Mechanism of Action
This peptide acts as an anti-edematous agent by inhibiting Angiotensin I-Converting Enzyme (ACE) to improve microcirculation and prevent fluid accumulation. Additionally, it reduces glycation and enhances Superoxide Dismutase activity to protect collagen and maintain elasticity.
Research
Clinical Evidence
High confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable in aqueous solutions; integrate into formulations during the cooling phase (below 40-45°C) to preserve peptide integrity. Store away from light due to its hygroscopic nature.
Conflicts
- Strong oxidizing agents
- Strong acids/bases (outside pH 2.0-7.0)
- High heat (>45°C) during processing
Safety
Safety Profile
Generally considered safe and non-toxic for cosmetic topical use, with widespread industry utilization at low pure peptide concentrations. Potential irritation is noted only in the pure, undiluted powder form.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Acetyl Tetrapeptide-5 is a valuable ingredient for addressing under-eye bags, puffiness, and improving elasticity, supported by robust clinical data and excellent skin compatibility.
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