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ACETYL TETRAPEPTIDE-27.

Valuable / SKIN CONDITIONING

A synthetic skin-conditioning peptide, Acetyl Tetrapeptide-27 is a modified Tetrapeptide-27 known for its role in advanced anti-aging skincare, particularly in prestige formulations like those from Estée Lauder.

Skin Conditioning Collagen Boosting Anti-aging

Science

This peptide functions as a skin-conditioning agent, supporting longevity pathways by stimulating biological signals. It promotes collagen synthesis, enhances skin barrier renewal, and targets sirtuin-related aging markers.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Studies within the SIRTIVITY-LP complex indicate it contributes to boosting collagen production by up to 174% and reactivating skin renewal processes.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Heat-sensitive, integrate below 40°C during cooling phase. Optimal stability is maintained in an acidic to neutral pH environment.

Conflicts

  • Strong oxidizing agents
  • Strongly acidic environments (pH < 3.5)
  • Strongly alkaline environments (pH > 8.0)
  • Proteolytic enzymes

Safety

CIR Status
Not reviewed
Sensitization risk Low

Lacks formal safety reviews from CIR/SCCS. It is dermatologically tested in prestige products, adhering to general synthetic peptide safety standards.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A valuable anti-aging peptide that supports skin longevity pathways and collagen production, best utilized within formulations designed for optimal stability and efficacy.


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