Science
Mechanism of Action
This peptide activates endogenous skin repair, primarily through promoting melanophagy, the autophagic degradation of melanosomes. It also inhibits tyrosinase activity, thereby reducing melanin synthesis and improving skin luminosity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical evaluations and in vitro tests indicate that at 0.01% - 0.05%, it effectively reduces melanin production and brightens skin tone by targeting the melanophagy pathway, resulting in a visible reduction of freckles and blemishes.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
For optimal peptide integrity, incorporate into the aqueous phase of formulations during the cool-down phase, specifically below 40°C.
Conflicts
- strong oxidizing agents
- strong acids
- strong bases
- proteolytic enzymes
Safety
Safety Profile
Listed in the EU Cosmetic Ingredient Glossary (CosIng) as a skin conditioning agent. No specific safety restrictions or maximum usage levels have been established by CIR or SCCS.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This peptide is a valuable ingredient for targeting hyperpigmentation and enhancing skin luminosity across all skin types, demonstrating low irritation and clear efficacy.
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References
Sources