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ACETYL SH-PENTAPEPTIDE-35.

Valuable / SKIN CONDITIONING

Acetyl sh-Pentapeptide-35 is a biomimetic peptide designed to mimic the activity of Sirtuins, promoting cellular longevity. It is utilized for its anti-aging benefits and overall skin conditioning properties.

skin conditioning anti-aging

Science

This peptide stimulates the skin's natural defense and repair mechanisms, shielding DNA from oxidative stress. It often leverages diamond particle conjugation (Diamond Sirt complex) for enhanced stabilization and delivery.


Research

Medium confidence
Effective range N/A
Optimal

0.5%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

Highly stable when delivered via silica/diamond microspheres. It requires a slightly acidic to neutral pH range (3.0-7.0) to prevent degradation.

Conflicts

  • Strong oxidizing agents
  • Proteolytic enzymes
  • Highly acidic (pH < 3.0) or highly alkaline (pH > 8.0) environments

Safety

CIR Status
Not reviewed
Sensitization risk Low

There is no formal CIR or SCCS safety assessment. However, it is widely used in high-end cosmetic formulations and generally considered safe at typical usage levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A valuable biomimetic peptide, Acetyl sh-Pentapeptide-35 offers promising anti-aging and skin-calming benefits with excellent compatibility across all skin types.


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