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Ingredient directory

Acetyl Sh-oligopeptide-92 Sp

A synthetic biomimetic peptide, Acetyl sh-Oligopeptide-92 SP functions as a skin and hair conditioning agent. It is an acetylated derivative of sh-Oligopeptide-92, designed to enhance skin repair and resilience.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Skin Conditioning Skin Protecting Hair Conditioning

Science

This peptide acts as a biomimetic messenger, signaling skin cells by mimicking natural growth factors. It binds to specific receptors to activate repair processes, stimulating the production of extracellular matrix proteins like collagen and elastin, and strengthening the skin barrier.


Research

Medium confidence
Effective range 0.001–0.01%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Stable in aqueous solutions within a neutral pH range (pH 5.0-7.0). It is heat-sensitive and should be incorporated during the cooling phase (<40°C) to prevent denaturation.

Conflicts

  • Strong oxidizing agents
  • Proteolytic enzymes
  • Highly acidic (pH <4) or highly alkaline (pH >8) environments

Safety

CIR Status
Not reviewed
Sensitization risk Low

Listed in the EU Cosmetic Ingredient Database (CosIng). Generally considered safe for topical use due to low molecular weight and high biocompatibility.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Acetyl sh-Oligopeptide-92 SP is a valuable biomimetic peptide for enhancing skin repair and resilience, supported by its mechanism and in-vitro efficacy, with low irritancy and good compatibility across all skin types.


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References

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