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ACETYL SH-OLIGOPEPTIDE-77 AMIDE.

Valuable / SKIN CONDITIONING

ACETYL SH-OLIGOPEPTIDE-77 AMIDE is a synthetic, acetylated peptide engineered for enhanced stability and optimal skin penetration. It functions as a signaling peptide to stimulate skin regeneration and modulate melanin production.

Skin conditioning Anti-aging Brightening Skin regeneration Hair follicle stimulation

Science

This peptide biomimics natural growth factors and collagen fragments, activating cellular processes to strengthen skin structure and boost regeneration. It also actively modulates melanin production, contributing to a noticeable brightening effect.


Research

Medium confidence
Effective range 0.009–4.628%
Optimal

N/A

Key findings

  1. 01 Indicated in a hair care growth factor complex (0.009% - 4.628%) for promoting hair follicle cell regeneration and growth.
  2. 02 Marketed in skincare serums and eye creams to brighten dark spots, protect against sun damage, and promote firmer, smoother skin by targeting pigmentation.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Acetylation and amidation significantly enhance its stability against proteolytic degradation. It remains stable in aqueous solutions but is intolerant to strong alkalis.

Conflicts

  • Strong alkalis
  • Strong oxidizing agents
  • Proteolytic enzymes

Safety

CIR Status
Not reviewed
Sensitization risk Low

Listed in the EU CosIng database as a skin conditioning agent without specific usage restrictions. It is generally considered safe in the low concentrations typical for cosmetic use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This acetylated growth factor biomimetic peptide offers valuable anti-aging, skin regeneration, and brightening benefits, making it a key component for advanced skincare formulations.


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