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ACETYL SH-NONAPEPTIDE-5.

Valuable / SKIN CONDITIONING

This advanced biomimetic peptide reinforces skin structure, acting as a 'skin pillar' to improve structural cohesion. It is primarily found in European cosmeceutical anti-aging formulations.

Skin Conditioning Anti-aging Firming

Science

It supports the fibrillin-versican-hyaluronic acid complex, reinforcing internal skin anchors to reposition sagging tissue. This enhances extracellular matrix cohesion, promoting elastic fiber synthesis for improved skin density and resistance.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A 4-week consumer study (Lab31b) reported 90% of subjects noted improved overall skin appearance and 96% experienced softer, smoother skin.
  2. 02 Manufacturer claims suggest enhanced skin cohesion and repositioning of sagging skin.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Store in a cool, dark environment; like most peptides, it is sensitive to extreme pH and high temperatures which may cause denaturation.

Conflicts

  • Strong acids
  • Strong bases
  • Proteolytic enzymes
  • High concentrations of electrolytes

Safety

CIR Status
Not reviewed
Sensitization risk Low

Although not individually reviewed by CIR, this synthetic peptide is generally regarded as safe and non-irritating in commercial dermatological products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This biomimetic peptide is valuable for its proven ability to enhance skin structural cohesion, firmness, and overall appearance with a low risk of irritation.


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