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Moumoujus

ACETYL SH-HEXAPEPTIDE-8 SP.

Valuable / SKIN CONDITIONING, SKIN PROTECTING

Acetyl sh-Hexapeptide-8 SP is a synthetic peptide produced via biotechnology, primarily functioning as a skin conditioning and protecting agent. It visibly reduces the appearance of expression lines and enhances overall skin texture.

Summary

Skin conditioning Skin protecting Anti-aging Expression line treatment

Science

Mechanism of Action

This peptide inhibits neurotransmitters by targeting the SNAP-25 protein, similar to Acetyl Hexapeptide-8, thereby reducing muscle contractions responsible for dynamic wrinkles. The 'SP' variant suggests enhanced stability or purity for professional formulations.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–5%
Optimal

0.5%

Key findings

  1. 01 Related hexapeptides (Argireline type) have shown up to a 30% reduction in wrinkle depth over 30 days in concentrations between 0.5-5%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 6
0 7 14

Stability

As a peptide, it is sensitive to temperatures above 40°C and extreme pH levels, which can lead to hydrolysis and degradation.

Conflicts

  • Strong oxidizing agents
  • Highly acidic (pH < 3.0) or alkaline (pH > 7.0) environments
  • Proteolytic enzymes

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Listed as safe for use in EU CosIng and Korean cosmetic databases. While not individually reviewed by CIR, its parent compound, Acetyl Hexapeptide-8, is deemed safe.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A valuable synthetic peptide for all skin types, effectively conditioning and protecting the skin while significantly reducing the appearance of expression lines.

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