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ACETYL SH-DECAPEPTIDE-2 AMIDE.

Valuable / SKIN CONDITIONING

Acetyl sh-Decapeptide-2 Amide is a biomimetic peptide engineered to promote cellular rejuvenation and combat signs of aging. It visibly reduces wrinkle depth and improves skin firmness, providing comprehensive skin conditioning.

skin conditioning anti-aging

Science

This synthetic signal peptide mimics Basic Fibroblast Growth Factor (bFGF), stimulating fibroblasts to produce essential collagen and elastin. Its acetylated and amidated structure ensures enhanced stability and optimal skin penetration within the skin.


Research

Medium confidence
Effective range 0.1–1%
Optimal

1%

Key findings

  1. 01 Manufacturer data indicates significant reduction in wrinkle depth and improved skin firmness after 28 days, attributed to enhanced cellular rejuvenation and collagen production.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 7.5
0 7 14

Stability

Stable under standard storage conditions (cool, dry, protected from light). It should be integrated during the cool-down phase of formulation, below 40°C, to prevent thermal degradation.

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong bases
  • Proteolytic enzymes

Safety

CIR Status
Not reviewed
Sensitization risk Low

While not individually reviewed by CIR, similar decapeptides are generally considered safe. Standard assessments indicate low toxicity and no significant sensitization risk.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This biomimetic peptide effectively targets signs of aging by boosting collagen and elastin production, making it a valuable addition for firming and wrinkle reduction.


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