Science
Mechanism of Action
This Sirtuin-1 (SIRT1) analog peptide regulates cellular aging, enhances DNA repair, and protects against oxidative stress. When complexed with diamond nanoparticles, its bioavailability and stability are optimized to stimulate collagen and GAGs synthesis.
Research
Clinical Evidence
Medium confidence2%
Key findings
- 01 In-vitro testing demonstrated a significant increase in Sirtuin-1 expression, boosting cellular longevity and DNA repair.
- 02 A clinical evaluation revealed a 169% increase in GAGs synthesis and a 100% reduction in periorbital wrinkles over 4 weeks.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Highly stable when conjugated with diamond/silica particles. Incorporate during the cooling phase (below 40°C) to prevent peptide denaturation.
Conflicts
- Strong oxidizing agents
- Proteolytic enzymes
- Extreme pH values (<4.0 or >8.0)
Safety
Safety Profile
Lacks formal CIR assessment, yet it is widely used in commercial formulations up to 2% (complexed form) and generally considered non-toxic and non-sensitizing.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Acetyl Pentapeptide-35 is a valuable anti-aging peptide that effectively enhances cellular longevity and reduces wrinkles, demonstrating good compatibility across all skin types.
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