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Moumoujus

ACETYL MONOFLUOROHEPTAPEPTIDE-1.

Valuable / SKIN PROTECTING

A synthetic biomimetic peptide engineered to mimic the muscle-relaxing effects of injectable neurotoxins through topical application. This fluorinated heptapeptide targets voltage-gated sodium channels to temporarily reduce facial muscle contractions, offering a non-invasive approach to smoothing dynamic wrinkles.

Summary

skin-protecting cell-communicating ingredient anti-aging

Science

Mechanism of Action

Functions as a selective voltage-gated sodium channel blocker, specifically targeting NaV 1.4 channels to interrupt neuromuscular transmission signals that cause facial muscle contractions, resulting in temporary muscle relaxation and wrinkle reduction

Research

Clinical Evidence

Medium confidence
Effective range 1–5%
Optimal

3%

Key findings

  1. 01 Related conopeptide studies show significant wrinkle depth and surface roughness reduction within 2 hours of single application

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Given the 1-5% recommended use level and peptide stability requirements, concentrations below 0.1% are likely insufficient for neuromuscular modulation effects

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Exhibits high stability in aqueous systems but requires cool-phase addition below 30-40°C to preserve peptide structural integrity

Synergies

  • hyaluronic acid
  • glycerin
  • other peptides

Conflicts

  • strong oxidizing agents
  • proteolytic enzymes
  • extreme pH conditions

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

Generally recognized as safe due to high molecular weight limiting systemic absorption, though specific CIR evaluation pending

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A scientifically-designed peptide offering topical muscle relaxation benefits with excellent safety profile and universal skin type compatibility.

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