Science
Mechanism of Action
Functions through high concentrations of polyphenols and gallotannins, particularly Ginnalin A, which inhibit collagenase and elastase enzymes to preserve structural proteins. Simultaneously reduces oxidative stress in keratinocytes, suppresses tyrosinase activity to control melanin production, and strengthens barrier function through cellular protection pathways.
Research
Clinical Evidence
High confidence0.1%
Key findings
- 01 56-day trial at 0.1% concentration showing 100% improvement in flexibility and hydration, >90% improvement in firmness and texture
- 02 In vitro study at 50 μg/mL demonstrating significant oxidative stress reduction and melanogenesis inhibition in human keratinocytes
Transparency
Dusting Analysis
As a specialized botanical extract with documented efficacy at 0.1%, concentrations below 0.01% likely provide minimal benefits and may indicate formulation padding rather than therapeutic intent.
The Formula
Formulation
Stability
Maintains stability in aqueous systems; polyphenol content vulnerable to degradation from oxidizing conditions and alkaline pH environments above 7.0
Synergies
- Other antioxidants for enhanced protection
- Peptides for complementary anti-aging effects
- Barrier-supporting ceramides and lipids
Conflicts
- Strong oxidizing agents
- Highly alkaline formulations (pH > 7.0)
Safety
Safety Profile
No toxicity observed in cellular studies up to 100 μg/mL; similar Acer genus extracts have established safety records in cosmetic applications without significant adverse reports
Your Skin
Skin Compatibility
Our Assessment
Verdict
A clinically substantiated botanical extract offering multi-modal anti-aging benefits with excellent safety profile and broad skin type compatibility.
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References
Sources